THE ANTIBACTERIAL ACTIVITY OF AZADARICHTA INDICA (NEEM PLANT)
ABSTRACT
The antibacterial effect of Azadirachta indica (neem plant) against Pseudomonas aeruginosa, Klebsiella ozanae, Staphylococcus aureus and Escherichia coli was determined using the agar cup plate techniques. The phytochemical components of A. indica showed the presence of saponin and phlobatanin and the absence of alkaloids, tannis, phenolics, plycosides, flavonoids, and triterpenes, the result showed that the test organisms were susceptible to 500mg/ml, 50mg/ml and 5mg/ml of the plant extract. The minmum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined, the result showed that the MIC and MBC were 5mg and 50mg respectively for Pseudomonas aeruginosa, K. ozanae, Staphylococcus aureus and Escherichia coli. The result of the study suggest that extracts of A. indica could be suitable for the treatment of various infections caused by P. aeruginosa, K. ozanae, S. aureus and E. coli.
